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Rheumatoid Arthritis

Rheumatoid arthritis is a chronic, autoimmune, inflammatory disease. Since it can affect multiple organs of the human body, it is classified as a systemic disease. Rheumatoid arthritis begins usually in middle age and women are more likely to develop it compared to men. A positive for the disease family history, smoking and obesity are among the risk factors for the onset of the disease. If left untreated it can cause a series of other complications such as osteoporosis, carpal tunnel syndrome, lung disease and lymphoma.

 

Diagnosis of Real Causes & Treatment of Rheumatoid Arthritis

  • Gradual restoration of cellular function
  • Personalized therapeutic protocols, without chemical residues and excipients
  • Treating the real causes
  • Therapeutic formulas that work alone or in combination with any other medication
  • Adopting a Molecular / Therapeutic Nutrition Plan

 

Rheumatoid Arthritis

 

Rheumatoid arthritis manifests through symptoms like joint pain and swelling, fever, fatigue, joint stiffness (especially in the morning) and loss of appetite. These symptoms may come and go and their severity may differ over time.

 

Your Health Specialist will address a series of targeted questions to you, to assess whether your symptoms could be indicative of Rheumatoid Arthritis. Then your specialist may recommend a specialized blood or antibodies test, an X-ray or MRI scan or other molecular-level diagnostic tests to confirm the diagnosis. Your personalized treatment plan will be based upon the diagnostic tests results, the symptoms described and your medical history overall.

This treatment plan may be accompanied by a Molecular Nutrition program that will be compiled after a distinct consultation with our Molecular Nutritionist and will aim towards achieving even higher levels of health and well-being along with alleviating not only the symptoms but the true causes of Rheumatoid Arthritis.

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References


  • Verma MK, Sobha K. Understanding the major risk factors in the beginning and the progression of rheumatoid arthritis: current scenario and future prospects. Inflamm Res. 2015;64(9):647-659. doi:1007/s00011-015-0843-8
  • Hootman JM, Helmick CG, Barbour KE, Theis KA, Boring MA. Updated projected prevalence of self-reported doctor-diagnosed arthritis and arthritis-attributable activity limitation among US adults, 2015-2040. Arthritis Rheumatol. 2016;68(7):1582-1587. doi:1002/art.39692
  • MacGregor AJ, Snieder H, Rigby AS, et al. Characterizing the quantitative genetic contribution to rheumatoid arthritis using data from twins. Arthritis Rheum. 2000;43(1):30-37. doi:1002/1529-0131(200001)43:1<30::AID-ANR5>3.0.CO;2-B
  • Araki Y, Mimura T. The mechanisms underlying chronic inflammation in rheumatoid arthritis from the perspective of the epigenetic landscape. J Immunol Res. 2016;2016:6290682. doi:1155/2016/6290682
  • Glant TT, Mikecz K, Rauch TA. Epigenetics in the pathogenesis of rheumatoid arthritis. BMC Med. 2014;12:35. doi:1186/1741-7015-12-35
  • Nielen MM, van Schaardenburg D, Reesink HW, et al. Specific autoantibodies precede the symptoms of rheumatoid arthritis: a study of serial measurements in blood donors. Arthritis Rheum. 2004;50(2):380-386. doi:1002/art.20018
  • Tracy A, Buckley CD, Raza K. Pre-symptomatic autoimmunity in rheumatoid arthritis: when does the disease start? Semin Immunopathol. 2017;39(4):423-435. doi:1007/s00281-017-0620-6
  • Rakieh C, Nam JL, Hunt L, et al. Predicting the development of clinical arthritis in anti-CCP positive individuals with non-specific musculoskeletal symptoms: a prospective observational cohort study. Ann Rheum Dis. 2015;74(9):1659-1666. doi:1136/annrheumdis-2014-205227
  • Ramos-Remus C, Castillo-Ortiz JD, Aguilar-Lozano L, et al. Autoantibodies in prediction of the development of rheumatoid arthritis among healthy relatives of patients with the disease. Arthritis Rheumatol. 2015;67(11):2837-2844. doi:1002/art.39297
  • Deane KD, Demoruelle MK, Kelmenson LB, Kuhn KA, Norris JM, Holers VM. Genetic and environmental risk factors for rheumatoid arthritis. Best Pract Res Clin Rheumatol. 2017;31(1):3-18. doi:1016/j.berh.2017.08.003
  • Harrison M, Spooner L, Bansback N, et al. Preventing rheumatoid arthritis: preferences for and predicted uptake of preventive treatments among high risk individuals. PLoS One. 2019;14(4):e0216075. doi:1371/journal.pone.0216075
  • Hunt L, Emery P. Defining populations at risk of rheumatoid arthritis: the first steps to prevention. Nat Rev Rheumatol. 2014;10(9):521-530. doi:1038/nrrheum.2014.82
  • Paul BJ, Kandy HI, Krishnan V. Pre-rheumatoid arthritis and its prevention. Eur J Rheumatol. 2017;4(2):161-165. doi:5152/eurjrheum.2017.16006
  • Gerlag DM, Norris JM, Tak PP. Towards prevention of autoantibody-positive rheumatoid arthritis: from lifestyle modification to preventive treatment. Rheumatology (Oxford). 2016;55(4):607-614. doi:1093/rheumatology/kev347
  • Silman AJ, Newman J, MacGregor AJ. Cigarette smoking increases the risk of rheumatoid arthritis. Results from a nationwide study of disease-discordant twins. Arthritis Rheum. 1996;39(5):732-735. doi:1002/art.1780390504
  • Stolt P, Bengtsson C, Nordmark B, et al. Quantification of the influence of cigarette smoking on rheumatoid arthritis: results from a population based case-control study, using incident cases. Ann Rheum Dis. 2003;62(9):835-841. doi:1136/ard.62.9.835
  • Hutchinson D, Shepstone L, Moots R, Lear JT, Lynch MP. Heavy cigarette smoking is strongly associated with rheumatoid arthritis (RA), particularly in patients without a family history of RA. Ann Rheum Dis. 2001;60(3):223-227. doi:1136/ard.60.3.223
  • Anderson R, Meyer PW, Ally MM, Tikly M. Smoking and air pollution as pro-inflammatory triggers for the development of rheumatoid arthritis. Nicotine Tob Res. 2016;18(7):1556-1565. doi:1093/ntr/ntw030
  • Kharlamova N, Jiang X, Sherina N, et al. Antibodies to Porphyromonas gingivalis indicate interaction between oral infection, smoking, and risk genes in rheumatoid arthritis etiology. Arthritis Rheumatol. 2016;68(3):604-613. doi:1002/art.39491
  • Pretorius E, Akeredolu OO, Soma P, Kell DB. Major involvement of bacterial components in rheumatoid arthritis and its accompanying oxidative stress, systemic inflammation and hypercoagulability. Exp Biol Med (Maywood). 2017;242(4):355-373. doi:1177/1535370216681549
  • Lu B, Hiraki LT, Sparks JA, et al. Being overweight or obese and risk of developing rheumatoid arthritis among women: a prospective cohort study. Ann Rheum Dis. 2014;73(11):1914-1922. doi:1136/annrheumdis-2014-205459
  • Sparks JA, Chang SC, Nguyen US, et al. Weight change during the early rheumatoid arthritis period and risk of subsequent mortality in women with rheumatoid arthritis and matched comparators. Arthritis Rheumatol. 2018;70(1):18-29. doi:1002/art.40346
  • Baker JF, Von Feldt J, Mostoufi-Moab S, et al. Deficits in muscle mass, muscle density, and modified associations with fat in rheumatoid arthritis. Arthritis Care Res (Hoboken). 2014;66(11):1612-1618. doi:1002/acr.22328
  • Hanaoka BY, Ithurburn MP, Rigsbee CA, et al. Chronic inflammation in rheumatoid arthritis and mediators of skeletal muscle pathology and physical impairment: a review. Arthritis Care Res (Hoboken). 2019;71(2):173-177. doi:1002/acr.23775
  • Bärebring L, Winkvist A, Gjertsson I, Lindqvist HM. Poor dietary quality is associated with increased inflammation in Swedish patients with rheumatoid arthritis. Nutrients. 2018;10(10):E1535. doi:3390/nu10101535
  • Essouma M, Noubiap JJ. Is air pollution a risk factor for rheumatoid arthritis? J Inflamm (Lond). 2015;12:48. doi:1186/s12950-015-0092-1
  • Jung CR, Hsieh HY, Hwang BF. Air pollution as a potential determinant of rheumatoid arthritis: a population-based cohort study in Taiwan. 2017;28(Suppl 1):S54-S59. doi:10.1097/EDE.0000000000000732
  • Shin J, Lee J, Lee J, Ha EH. Association between exposure to ambient air pollution and rheumatoid arthritis in adults. Int J Environ Res Public Health. 2019;16(7):E1227. doi:3390/ijerph16071227
  • Sigaux J, Biton J, André E, Semerano L, Boissier MC. Air pollution as a determinant of rheumatoid arthritis. Joint Bone Spine. 2019;86(1):37-42. doi:1016/j.jbspin.2018.03.001
  • Araki Y, Mimura T. The mechanisms underlying chronic inflammation in rheumatoid arthritis from the perspective of the epigenetic landscape. J Immunol Res. 2016;2016:6290682. doi:1155/2016/6290682
  • Zaccardelli A, Friedlander HM, Ford JA, Sparks JA. Potential of lifestyle changes for reducing the risk of developing rheumatoid arthritis: is an ounce of prevention worth a pound of cure? Clin Ther. 2019;41(7):1323-1345. doi:1016/j.clinthera.2019.04.021
  • He J, Wang Y, Feng M, et al. Dietary intake and risk of rheumatoid arthritis—a cross section multicenter study. Clin Rheumatol. 2016;35(12):2901-2908. doi:1007/s10067-016-3383-x
  • Vadell AKE, Bärebring L, Hulander E, Gjertsson I, Lindqvist HM, Winkvist A. Anti-inflammatory diet in rheumatoid arthritis (ADIRA) – a randomized, controlled crossover trial indicating effects on disease activity. Am J Clin Nutri. 2020;111(6):1203-1213. doi:1093/ajcn/nqaa019
  • Philippou E, Nikiphorou E. Are we really what we eat? Nutrition and its role in the onset of rheumatoid arthritis. Autoimmun Rev. 2018;17(11):1074-1077. doi:1016/j.autrev.2018.05.009
  • Gioia C, Lucchino B, Tarsitano MG, Iannuccelli C, Di Franco M. Dietary habits and nutrition in rheumatoid arthritis: can diet influence disease development and clinical manifestations? Nutrients. 2020;12(5):1456. doi:3390/nu12051456
  • Asteriou E, Gkoutzourelas A, Mavropoulos A, Katsiari C, Sakkas LI, Bogdanos DP. Curcumin for the management of periodontitis and early ACPA-positive rheumatoid arthritis: killing two birds with one stone. 2018;10(7):E908. doi:10.3390/nu10070908