fbpx
+44 208 068 4002

Insulin: The “key” to normal weight and good health

Weight Loss Insulin

25 Feb Insulin: The “key” to normal weight and good health

Posted at 14:16h in Metabolic Diseases, Molecular Nutrition, Nutrition by

If you  blame yourself for not losing weight, for constantly accumulating fat, despite the deprivations, calorie counting, fat restriction and running at the gym, it’s time to stop doing it and instead find the real culprit for the extra pounds that persist.

The obesity epidemic and its consequences have specific causes.

Since 1980, people have been following the “experts”, eating relatively little protein, less fat and clearly more carbohydrates because they are supposed to be a “good source of energy”.

The result is that obese people are becoming more and more (250% increase!). In the beginning they may lose a little body fat but also a lot of muscles and bones. Then they quickly regain all the lost weight – and most times even more -, resulting in obesity, and a worse state of health.

Obesity can transform into a pre-diabetic condition and is a disease-causing cause. For every person suffering from diabetes, four pre-diabetic and most commonly obese people exist – The quality and quantity of the food we consume, shapes the hormonal environment inside our body for the next 5-6 hours after a meal, but also in the long run affecting the future course of our health.

Accumulation of body fat is hormonally governed, and in order to occur, requires the mediation of an extremely important hormonal force, insulin. Without insulin, no fat is produced in our body and no dietary fat enters our cells. On the other hand too much insulin circulating in the blood (hyperinsulinemia), urges our body to accumulate body fat even if we reduce calories or fat intake.

The contribution of Glucose & Insulin is therefore important, since it regulates our overall health and hormonal balance. A careful and unbiased study of history and research findings shows that a person is not obese, because he consumes a lot of calories or fat or because he does not exercise, as conventional dietology incorrectly assumes, but because he eats unnecessary calories deriving from carbohydrates and processed foods. .

One of the most important mistakes of conventional dietology is that in its course it has ignored the greatest biological force on the planet, namely our hormones, thus resulting in obesity and diabetes.

So the forgotten truth that needs to be recalled is that in order for our body to accumulate fat, insulin needs to mediate. Without insulin, no fat is produced in our body and no dietary fat enters our cells.

Too much insulin on the other hand will cause the accumulation of body fat even if we reduce the amount of food we consume.

Foods rich in sugar (glucose) and processed carbohydrates will cause a rapid increase of glucose levels and in a next step an increase in insulin levels too.

What we need to remember is that eating healthy and hormonally smart, will grant us a long life without the implications and consequences of obesity and diabetes.

 

 

Dr. Nikoleta Koini, M.D.

Doctor of Functional, Preventive, Anti-ageing and Restorative Medicine.
Diplomate and Board Certified in Anti-aging, Preventive, Functional and Regenerative Medicine from A4M (American Academy in Antiaging Medicine).

 

References:

  • Editor (2019-01-15). “The discovery and development of insulin as a medical treatment can be traced back to the 19th century”. Diabetes. Retrieved 2020-02-17.
  • Wang W, Shi Q, Guo T, Yang Z, Jia Z, Chen P, Zhou C (June 2016). “PDX1 and ISL1 differentially coordinate with epigenetic modifications to regulate insulin gene expression in varied glucose concentrations”. Molecular and Cellular Endocrinology. 428: 38–48. doi:10.1016/j.mce.2016.03.019. PMID 26994512.
  • “Insulin human”. PubChem. Retrieved 26 February 2019.
  • Fu Z, Gilbert ER, Liu D (January 2013). “Regulation of insulin synthesis and secretion and pancreatic Beta-cell dysfunction in diabetes”. Current Diabetes Reviews. 9 (1): 25–53. doi:10.2174/157339913804143225. PMC 3934755. PMID 22974359.
  • Lorenzo C, Wagenknecht LE, Rewers MJ, Karter AJ, Bergman RN, Hanley AJ, Haffner SM (September 2010). “Disposition index, glucose effectiveness, and conversion to type 2 diabetes: the Insulin Resistance Atherosclerosis Study (IRAS)”. Diabetes Care. 33 (9): 2098–103. doi:10.2337/dc10-0165. PMC 2928371. PMID 20805282.
  • Sarode BR, Kover K, Tong PY, Zhang C, Friedman SH (November 2016). “Light Control of Insulin Release and Blood Glucose Using an Injectable Photoactivated Depot”. Molecular Pharmaceutics. 13 (11): 3835–3841. doi:10.1021/acs.molpharmaceut.6b00633. PMC 5101575. PMID 27653828.
  • Zheng C, Liu Z (June 2015). “Vascular function, insulin action, and exercise: an intricate interplay”. Trends in Endocrinology and Metabolism. 26 (6): 297–304. doi:10.1016/j.tem.2015.02.002. PMC 4450131. PMID 25735473.
  • Comninos AN, Jayasena CN, Dhillo WS (2014). “The relationship between gut and adipose hormones, and reproduction”. Human Reproduction Update. 20 (2): 153–74. doi:10.1093/humupd/dmt033. PMID 24173881. S2CID 18645125.
  • Gatta-Cherifi B, Cota D (February 2016). “New insights on the role of the endocannabinoid system in the regulation of energy balance”. International Journal of Obesity. 40 (2): 210–19. doi:10.1038/ijo.2015.179. PMID 26374449. S2CID 20740277.
  • Yanai H, Adachi H, Katsuyama H, Moriyama S, Hamasaki H, Sako A (February 2015). “Causative anti-diabetic drugs and the underlying clinical factors for hypoglycemia in patients with diabetes”. World Journal of Diabetes. 6 (1): 30–6. doi:10.4239/wjd.v6.i1.30. PMC 4317315. PMID 25685276.
  • Macdonald IA (November 2016). “A review of recent evidence relating to sugars, insulin resistance and diabetes”. European Journal of Nutrition. 55 (Suppl 2): 17–23. doi:10.1007/s00394-016-1340-8. PMC 5174139. PMID 27882410.
  • Saklayen MG (February 2018). “The Global Epidemic of the Metabolic Syndrome”. Current Hypertension Reports. 20 (2): 12. doi:10.1007/s11906-018-0812-z. PMC 5866840. PMID 29480368.
  • Vecchio, Ignazio; Tornali, Cristina; Bragazzi, Nicola Luigi; Martini, Mariano (2018-10-23). “The Discovery of Insulin: An Important Milestone in the History of Medicine”. Frontiers in Endocrinology. 9: 613. doi:10.3389/fendo.2018.00613. PMC 6205949. PMID 30405529.
  • Gast, Klaus; Schüler, Anja; Wolff, Martin; Thalhammer, Anja; Berchtold, Harald; Nagel, Norbert; Lenherr, Gudrun; Hauck, Gerrit; Seckler, Robert (2017). “Rapid-Acting and Human Insulins: Hexamer Dissociation Kinetics upon Dilution of the Pharmaceutical Formulation”. Pharmaceutical Research. 34 (11): 2270–2286. doi:10.1007/s11095-017-2233-0. PMC 5643355. PMID 28762200.
  • Silver, Bahendeka; Ramaiya, Kaushik; Andrew, Swai Babu; Fredrick, Otieno; Bajaj, Sarita; Kalra, Sanjay; Charlotte, Bavuma M.; Claudine, Karigire; Makhoba, Anthony (2018). “EADSG Guidelines: Insulin Therapy in Diabetes”. Diabetes Therapy. 9 (2): 449–492. doi:10.1007/s13300-018-0384-6. PMC 6104264. PMID 29508275.
  • Wong CY, Martinez J, Dass CR (2016). “Oral delivery of insulin for treatment of diabetes: status quo, challenges and opportunities”. The Journal of Pharmacy and Pharmacology. 68 (9): 1093–108. doi:10.1111/jphp.12607. PMID 27364922.
  • Shah RB, Patel M, Maahs DM, Shah VN (2016). “Insulin delivery methods: Past, present and future”. International Journal of Pharmaceutical Investigation. 6 (1): 1–9. doi:10.4103/2230-973X.176456. PMC 4787057. PMID 27014614.
  • Vecchio I, Tornali C, Bragazzi NL, Martini M (2018-10-23). “The Discovery of Insulin: An Important Milestone in the History of Medicine”. Frontiers in Endocrinology. 9: 613. doi:10.3389/fendo.2018.00613. PMC 6205949. PMID 30405529.
Tags:
, ,